The 5 Leading Industries in St. Louis

If you’re doing business in St. Louis, Missouri, then you know the importance of staying on top of the city’s economic pulse.

From national and international corporations to small, local businesses, it is necessary to understand which industries are experiencing growth and gain insight into who is leading the way.

With this in mind, we’ve put together an informative look at five biggest industries in St. Louis today—education, finance, healthcare services, auto manufacturing, and technology.

Dive deep into each one to learn more about them through their unique contributions to the local economy so that you can ensure your business remains competitive in the top industries in St. Louis.

5 Top Industries in St. Louis

A Closer Look at the Top Industries in St. Louis

St. Louis is the second largest city in the state of Missouri and is home to famous landmarks and institutions such as the Gateway Arch, the Mississippi River , the Missouri River, and the University of Missouri. With a total population of 2.8 million residents, opportunities for employment and talent abound.

Let’s take a closer look at some of the key St. Louis industries that are on their way to becoming some of the top industries in St. Louis today!

1. Auto Manufacturing

St. Louis has a thriving manufacturing industry, with fortune 500 automobile manufacturers such as Ford, Chrysler, and General Motors having major plants located here.

In the past decade, Missouri’s automotive facilities , including those in St. Louis and Kansas City, have received nearly $4 billion in investment.

Employing over 132.7 Thousand people through auto jobs in the state of Missouri, auto manufacturing continues to expand as one of the biggest industries in St. Louis today.

Aside from auto manufacturing, the city is also home to one of the world’s largest economies for manufacturing petroleum products , with companies like Schaefer Manufacturing, Energy Petroleum Corporation, and more located here.

2. Education

Prominent educational institutions like the University of Missouri make up for a large portion of the local economy, which accounts for an annual revenue of $547.2M alone.

Aside from this, there are over 10 community colleges located in the greater St. Louis region which accounts for a significant amount of talent pool in the trades and manufacturing industries.

A number of scholarships and grants are administered by the Missouri Department of Higher Education and Workforce Development as well, making the city an attractive option for post-secondary education.


Find out how managed IT is serving the local economy, helping businesses in St. Louis industries scale up.

Check out these other articles today:


3. Healthcare

As health reform turned into value-based payment, health systems acquired physician practices, hospitals, and other facilities across Greater St. Louis in order to expand.

A wide range of healthcare professionals are employed in Missouri’s 161 licensed hospitals , with the healthcare sector serving as one of St. Louis’ top industries .

Major healthcare system developments taking place in the area include:

  • An ambulatory center slated for 2024 being built by Tarlton Corp.
  • A $20 million expansion of Parkland Health Center’s campus
  • Siteman Cancer Center integrating new technologies and expanding proton therapy to treat cancer patients in the area

As one of St. Louis’ top industries , the healthcare sector, plays a vital role in facilitating employment opportunities, with educational research institutions like Washington University contributing a major role in medical research.

biggest industries in St. Louis
Image Credit: Washington University

4. Financial Services

In looking at the key industries in St. Louis , the role of financial services in economic development cannot be overlooked.

Financial services companies in St. Louis, MO include:

  • Brown Smith Wallace LLP
  • Edward D Jones & Co LP
  • Stifel Financial
  • Providence Financial

Over 84,000 people are employed by more than 7,900 businesses in the financial activities industry in the region. Find out why they look to NetGain Technologies as an IT company they can trust for the following information technology services:

Become a Leader Amongst Your Competitors with Managed & Professional IT

Focus On Running Your Business While We Handle Everything IT

5. Brewing

St. Louis is home to the one and only Anheuser Busch Brewing Company, founded in 1852 right in the home roots of our inland port city.

From 2021 to 2022, Anheuser Busch ‘s annual revenue increased by 6.41% to $57.786B. Employing over 19,000 people across the United States , the Anheuser Busch Inbev is one of the biggest companies in the world for beer and spirit production .

The historic brewery, located in Downtown St. Louis, has become a historical landmark and tourist attraction that features a beer museum, beer garden, giftshop, and classes.

Aside from this, other manufacturers in the area include:

  • Alpha Brewing Company
  • Rockwell Beer Company
  • 4 Hands Brewing Company

Find out Why Industry Leaders in St. Louis Rely On NetGain Technologies 

For over 39 years, NetGain Technologies has been a trusted partner in helping businesses in multiple industries in St. Louis expand their national footprints through the use of strategic professional and managed IT services.

With 190+ IT engineers on staff to help you resolve your information technology problems accordingly, you can concentrate on what you do best while we streamline everything IT related.


Find out how our proven processes can help you not only reach but surpass your business goals. Contact us today to learn more about our proven IT solutions and how they can help.

Related Posts

Does Generative AI Pose a Cybersecurity Threat?

There’s been a lot of attention on generative artificial intelligence (AI). Innovations like the AI-powered chatbot ChatGPT and other systems like VALL-E have brought the concept of generative AI to the forefront, showcasing both its advantages and potential drawbacks.

Read More »